Drink Coffee to Prevent Colon Cancer?
Drinking coffee may reduce the risk of developing colon cancer, a new study reports.
Researchers from Texas A&M University found that a compound called Trigonelline, commonly known as Trig and found in coffee beans, may be able to help prevent colon cancer.
The study reported that drinking coffee has been associated with the development of several endocrine-related cancers. It explained that the interpretation of the data has often been limited to the role that caffeine plays.
The authors defined Trig as a niacin-related compound that is a natural constituent of coffee, accounting for approximately one percent of the dry matter in roasted beans.
The study investigated whether Trig alters the actions of the phytoestrogen estradiol, which is one of the most potent naturally occurring estrogens in humans. The results of the study suggested that Trig itself may be a novel phytoestrogen.
The study authors explained that they are seeing very interesting information as far as tumor formation and the ability of phytoestrogens to prevent colon cancer formation.
The researchers warned that patients who are facing problems of estrogen dominance and other estrogen-related conditions such as breast cancer may want to avoid consuming the compound as it may increase their levels.
References:
- Allred KF, Yackley KM, Vanamala J, et al. Trigonelline is a novel phytoestrogen in coffee beans. J Nutr. 2009 Oct;139(10):1833-8.
- Je Y, Liu W, Giovannucci E. Coffee consumption and risk of colorectal cancer: a systematic review and meta-analysis of prospective cohort studies. Int J Cancer. 2009 Apr 1;124(7):1662-8.
- Colon Cancer Alliance. www.ccalliance.org. Copyright® 2009
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